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Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis

The local and systemic renin angiotensin system (RAS) influences the skeletal system micro-structure and metabolism. Studies suggested angiotensin 1-7 (Ang(1-7)) as the beneficial RAS molecule via Mas receptor activation. This study examines the function of Ang(1-7) in bone micro-architecture and me...

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Detalles Bibliográficos
Autores principales: Abuohashish, Hatem M., Ahmed, Mohammed M., Sabry, Dina, Khattab, Mahmoud M., Al-Rejaie, Salim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442122/
https://www.ncbi.nlm.nih.gov/pubmed/28536469
http://dx.doi.org/10.1038/s41598-017-02570-x