Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways

Cancer-induced cachexia, characterized by muscle wasting, is a lethal metabolic syndrome with undefined etiology. Current consensus is that multiple factors contribute to cancer-induced muscle wasting, and therefore therapy requires combinational strategies. Here, we show that Toll-like receptor 4 (...

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Detalles Bibliográficos
Autores principales: Zhang, Guohua, Liu, Zhelong, Ding, Hui, Miao, Hongyu, Garcia, Jose M., Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442131/
https://www.ncbi.nlm.nih.gov/pubmed/28536426
http://dx.doi.org/10.1038/s41598-017-02347-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442131/
https://www.ncbi.nlm.nih.gov/pubmed/28536426
http://dx.doi.org/10.1038/s41598-017-02347-2

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