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C1 Complex: An Adaptable Proteolytic Module for Complement and Non-Complement Functions
Complement C1 is the defining component of the classical pathway. Within the C1qC1r(2)C1s(2) complex, C1q functions as a molecular scaffold for C1r(2)C1s(2) and C1q binding to its ligands activates these two serine proteases. The classic C1q ligands are antigen-bound antibodies and activated C1s cle...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442170/ https://www.ncbi.nlm.nih.gov/pubmed/28596769 http://dx.doi.org/10.3389/fimmu.2017.00592 |