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Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection

In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality. Matrix metalloproteinase (MMP)-1 is a host enzyme critical for the d...

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Detalles Bibliográficos
Autores principales: Moores, Rachel C., Brilha, Sara, Schutgens, Frans, Elkington, Paul T., Friedland, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442172/
https://www.ncbi.nlm.nih.gov/pubmed/28596772
http://dx.doi.org/10.3389/fimmu.2017.00602