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Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection
In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality. Matrix metalloproteinase (MMP)-1 is a host enzyme critical for the d...
Autores principales: | Moores, Rachel C., Brilha, Sara, Schutgens, Frans, Elkington, Paul T., Friedland, Jon S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442172/ https://www.ncbi.nlm.nih.gov/pubmed/28596772 http://dx.doi.org/10.3389/fimmu.2017.00602 |
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