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Oral Bioavailability and Plasma Disposition of Pefloxacin in Healthy Broiler Chickens

The pharmacokinetics of pefloxacin after single 10 mg/kg BW intravenous (IV) and oral doses were studied in healthy broiler chickens. For 24 h, serial blood samples were obtained after IV and oral administration. Concentrations of pefloxacin and its major metabolite N-demethyl pefloxacin (norfloxaci...

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Detalles Bibliográficos
Autores principales: Martínez, María-Aránzazu, Ares, Irma, Rodríguez, José-Luis, Martínez, Marta, Martínez-Larrañaga, María-Rosa, Isea, Gerardo, Anadón, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442175/
https://www.ncbi.nlm.nih.gov/pubmed/28596959
http://dx.doi.org/10.3389/fvets.2017.00077