Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function

Complexin is a small soluble presynaptic protein that interacts with neuronal SNARE proteins in order to regulate synaptic vesicle exocytosis. While the SNARE-binding central helix of complexin is required for both the inhibition of spontaneous fusion and the facilitation of synchronous fusion, the...

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Detalles Bibliográficos
Autores principales: Snead, David, Lai, Alex L., Wragg, Rachel T., Parisotto, Daniel A., Ramlall, Trudy F., Dittman, Jeremy S., Freed, Jack H., Eliezer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442187/
https://www.ncbi.nlm.nih.gov/pubmed/28596722
http://dx.doi.org/10.3389/fnmol.2017.00154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442187/
https://www.ncbi.nlm.nih.gov/pubmed/28596722
http://dx.doi.org/10.3389/fnmol.2017.00154

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