Prognostic significance of the methylation of Wnt pathway antagonists—CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling—ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas

OBJECTIVES: Aberrations in Wnt and Shh signaling pathways are related to the pathogenesis of head and neck carcinomas, and their activation frequently results from epigenetic alterations. This study aimed to assess the frequency of methylation of negative regulators of Wnt signaling: CXXC4, DACT2, H...

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Detalles Bibliográficos
Autores principales: Paluszczak, Jarosław, Wiśniewska, Dorota, Kostrzewska-Poczekaj, Magdalena, Kiwerska, Katarzyna, Grénman, Reidar, Mielcarek-Kuchta, Daniela, Jarmuż-Szymczak, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442212/
https://www.ncbi.nlm.nih.gov/pubmed/27553089
http://dx.doi.org/10.1007/s00784-016-1946-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442212/
https://www.ncbi.nlm.nih.gov/pubmed/27553089
http://dx.doi.org/10.1007/s00784-016-1946-5

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