WIP1 phosphatase as pharmacological target in cancer therapy

DNA damage response (DDR) pathway protects cells from genome instability and prevents cancer development. Tumor suppressor p53 is a key molecule that interconnects DDR, cell cycle checkpoints, and cell fate decisions in the presence of genotoxic stress. Inactivating mutations in TP53 and other genes...

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Detalles Bibliográficos
Autores principales: Pecháčková, Soňa, Burdová, Kamila, Macurek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442293/
https://www.ncbi.nlm.nih.gov/pubmed/28439615
http://dx.doi.org/10.1007/s00109-017-1536-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442293/
https://www.ncbi.nlm.nih.gov/pubmed/28439615
http://dx.doi.org/10.1007/s00109-017-1536-2

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