Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast

Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein. Accordingly, Kinesin-5 inactivation results in force imbalance leading to monopolar spindle and chromosome segregation failure. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Rincon, Sergio A., Lamson, Adam, Blackwell, Robert, Syrovatkina, Viktoriya, Fraisier, Vincent, Paoletti, Anne, Betterton, Meredith D., Tran, Phong T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442317/
https://www.ncbi.nlm.nih.gov/pubmed/28513584
http://dx.doi.org/10.1038/ncomms15286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442317/
https://www.ncbi.nlm.nih.gov/pubmed/28513584
http://dx.doi.org/10.1038/ncomms15286

Ejemplares similares