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Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast

Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein. Accordingly, Kinesin-5 inactivation results in force imbalance leading to monopolar spindle and chromosome segregation failure. In...

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Detalles Bibliográficos
Autores principales:	Rincon, Sergio A., Lamson, Adam, Blackwell, Robert, Syrovatkina, Viktoriya, Fraisier, Vincent, Paoletti, Anne, Betterton, Meredith D., Tran, Phong T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442317/ https://www.ncbi.nlm.nih.gov/pubmed/28513584 http://dx.doi.org/10.1038/ncomms15286

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