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Zinc is a potent and specific inhibitor of IFN-λ3 signalling

Lambda interferons (IFNL, IFN-λ) are pro-inflammatory cytokines important in acute and chronic viral infection. Single-nucleotide polymorphisms rs12979860 and rs8099917 within the IFNL gene locus predict hepatitis C virus (HCV) clearance, as well as inflammation and fibrosis progression in viral and...

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Detalles Bibliográficos
Autores principales: Read, Scott A., O'Connor, Kate S., Suppiah, Vijay, Ahlenstiel, Chantelle L. E., Obeid, Stephanie, Cook, Kristina M., Cunningham, Anthony, Douglas, Mark W., Hogg, Philip J., Booth, David, George, Jacob, Ahlenstiel, Golo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442324/
https://www.ncbi.nlm.nih.gov/pubmed/28513591
http://dx.doi.org/10.1038/ncomms15245