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Biphalin, a Dimeric Enkephalin, Alleviates LPS-Induced Activation in Rat Primary Microglial Cultures in Opioid Receptor-Dependent and Receptor-Independent Manners

Neuropathic pain is relatively less responsive to opioids than other types of pain, which is possibly due to a disrupted opioid system partially caused by the profound microglial cell activation that underlines neuroinflammation. We demonstrated that intrathecally injected biphalin, a dimeric enkeph...

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Detalles Bibliográficos
Autores principales:	Popiolek-Barczyk, Katarzyna, Piotrowska, Anna, Makuch, Wioletta, Mika, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442438/ https://www.ncbi.nlm.nih.gov/pubmed/28573049 http://dx.doi.org/10.1155/2017/3829472

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