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CNOT4-Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication

Influenza A virus (IAV) RNA segments are individually packaged with viral nucleoprotein (NP) and RNA polymerases to form a viral ribonucleoprotein (vRNP) complex. We previously reported that NP is a monoubiquitinated protein which can be deubiquitinated by a cellular ubiquitin protease, USP11. In th...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Chen, Jeng, King-Song, Lai, Michael M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442456/
https://www.ncbi.nlm.nih.gov/pubmed/28536288
http://dx.doi.org/10.1128/mBio.00597-17