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Interactions between Th1 cells and Tregs affect regulation of hepatic fibrosis in biliary atresia through the IFN-γ/STAT1 pathway

Regulatory T cells (Tregs) and CD4(+) T helper (Th) cells have important roles in bile duct injury of biliary atresia (BA). However, their impacts on liver fibrosis are undefined. Between 2013 and 2016, 146 patients with various stages of BA were enrolled in this study. Peripheral blood, liver biops...

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Detalles Bibliográficos
Autores principales: Wen, Jie, Zhou, Ying, Wang, Jun, Chen, Jie, Yan, Wenbo, Wu, Jin, Yan, Junkai, Zhou, Kejun, Xiao, Yongtao, Wang, Yang, Xia, Qiang, Cai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442468/
https://www.ncbi.nlm.nih.gov/pubmed/28304404
http://dx.doi.org/10.1038/cdd.2017.31