Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke

Ring finger protein 146 (Iduna) facilitates DNA repair and protects against cell death induced by NMDA receptor-mediated glutamate excitotoxicity or by cerebral ischemia. Neuroprotectin D1 (NPD1), a docosahexaenoic acid (DHA)-derived lipid mediator, promotes cell survival under uncompensated oxidati...

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Detalles Bibliográficos
Autores principales: Belayev, Ludmila, Mukherjee, Pranab K, Balaszczuk, Veronica, Calandria, Jorgelina M, Obenaus, Andre, Khoutorova, Larissa, Hong, Sung-Ha, Bazan, Nicolas G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442474/
https://www.ncbi.nlm.nih.gov/pubmed/28430183
http://dx.doi.org/10.1038/cdd.2017.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442474/
https://www.ncbi.nlm.nih.gov/pubmed/28430183
http://dx.doi.org/10.1038/cdd.2017.55

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