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Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke
Ring finger protein 146 (Iduna) facilitates DNA repair and protects against cell death induced by NMDA receptor-mediated glutamate excitotoxicity or by cerebral ischemia. Neuroprotectin D1 (NPD1), a docosahexaenoic acid (DHA)-derived lipid mediator, promotes cell survival under uncompensated oxidati...
Autores principales: | Belayev, Ludmila, Mukherjee, Pranab K, Balaszczuk, Veronica, Calandria, Jorgelina M, Obenaus, Andre, Khoutorova, Larissa, Hong, Sung-Ha, Bazan, Nicolas G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442474/ https://www.ncbi.nlm.nih.gov/pubmed/28430183 http://dx.doi.org/10.1038/cdd.2017.55 |
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