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Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment
Neuroectoderm is an important neural precursor. However, chromatin remodeling and its epigenetic regulatory roles during the differentiation of human neuroectodermal cells (hNECs) from human embryonic stem cells (hESCs) remain largely unexplored. Here, we obtained hNECs through directed differentiat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442478/ https://www.ncbi.nlm.nih.gov/pubmed/28475175 http://dx.doi.org/10.1038/cdd.2017.62 |