Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment

Neuroectoderm is an important neural precursor. However, chromatin remodeling and its epigenetic regulatory roles during the differentiation of human neuroectodermal cells (hNECs) from human embryonic stem cells (hESCs) remain largely unexplored. Here, we obtained hNECs through directed differentiat...

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Detalles Bibliográficos
Autores principales: Du, Yanhua, Liu, Zhenping, Cao, Xinkai, Chen, Xiaolong, Chen, Zhenyu, Zhang, Xiaobai, Zhang, Xiaoqing, Jiang, Cizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442478/
https://www.ncbi.nlm.nih.gov/pubmed/28475175
http://dx.doi.org/10.1038/cdd.2017.62

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