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Intracellular product recycling in high succinic acid producing yeast at low pH

BACKGROUND: The metabolic engineering of Saccharomyces cerevisiae for the production of succinic acid has progressed dramatically, and a series of high-producing hosts are available. At low cultivation pH and high titers, the product transport can become bidirectional, i.e. the acid is reentering th...

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Detalles Bibliográficos
Autores principales: Wahl, S. Aljoscha, Bernal Martinez, Cristina, Zhao, Zheng, van Gulik, Walter M., Jansen, Mickel L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442661/
https://www.ncbi.nlm.nih.gov/pubmed/28535757
http://dx.doi.org/10.1186/s12934-017-0702-0