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Intracellular product recycling in high succinic acid producing yeast at low pH
BACKGROUND: The metabolic engineering of Saccharomyces cerevisiae for the production of succinic acid has progressed dramatically, and a series of high-producing hosts are available. At low cultivation pH and high titers, the product transport can become bidirectional, i.e. the acid is reentering th...
Autores principales: | Wahl, S. Aljoscha, Bernal Martinez, Cristina, Zhao, Zheng, van Gulik, Walter M., Jansen, Mickel L. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442661/ https://www.ncbi.nlm.nih.gov/pubmed/28535757 http://dx.doi.org/10.1186/s12934-017-0702-0 |
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