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Glyoxalase‐1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose‐Derived Stem Cells in Streptozotocin‐Induced Diabetic Mice Model of Critical Limb Ischemia

Adipose‐derived stem cell (ADSC)‐based therapy is promising for critical limb ischemia (CLI) treatment, especially in patients with diabetes. However, the therapeutic effects of diabetic ADSCs (D‐ADSCs) are impaired by the diabetes, possibly through intracellular reactive oxygen species (ROS) accumu...

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Detalles Bibliográficos
Autores principales: Peng, Zhiyou, Yang, Xinrui, Qin, Jinbao, Ye, Kaichuang, Wang, Xin, Shi, Huihua, Jiang, Mier, Liu, Xiaobing, Lu, Xinwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442730/
https://www.ncbi.nlm.nih.gov/pubmed/28170200
http://dx.doi.org/10.5966/sctm.2015-0380