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Glyoxalase‐1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose‐Derived Stem Cells in Streptozotocin‐Induced Diabetic Mice Model of Critical Limb Ischemia
Adipose‐derived stem cell (ADSC)‐based therapy is promising for critical limb ischemia (CLI) treatment, especially in patients with diabetes. However, the therapeutic effects of diabetic ADSCs (D‐ADSCs) are impaired by the diabetes, possibly through intracellular reactive oxygen species (ROS) accumu...
Autores principales: | Peng, Zhiyou, Yang, Xinrui, Qin, Jinbao, Ye, Kaichuang, Wang, Xin, Shi, Huihua, Jiang, Mier, Liu, Xiaobing, Lu, Xinwu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442730/ https://www.ncbi.nlm.nih.gov/pubmed/28170200 http://dx.doi.org/10.5966/sctm.2015-0380 |
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