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Human Adipose‐Derived Stem Cells Expanded Under Ambient Oxygen Concentration Accumulate Oxidative DNA Lesions and Experience Procarcinogenic DNA Replication Stress

Adipose‐derived stem cells (ADSCs) have led to growing interest in cell‐based therapy because they can be easily harvested from an abundant tissue. ADSCs must be expanded in vitro before transplantation. This essential step causes concerns about the safety of adult stem cells in terms of potential t...

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Detalles Bibliográficos
Autores principales: Bétous, Rémy, Renoud, Marie‐Laure, Hoede, Claire, Gonzalez, Ignacio, Jones, Natalie, Longy, Michel, Sensebé, Luc, Cazaux, Christophe, Hoffmann, Jean‐Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442744/
https://www.ncbi.nlm.nih.gov/pubmed/28170194
http://dx.doi.org/10.5966/sctm.2015-0401