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Regeneration of Articular Cartilage by Human ESC‐Derived Mesenchymal Progenitors Treated Sequentially with BMP‐2 and Wnt5a

The success of cell‐based therapies to restore joint cartilage requires an optimal source of reparative progenitor cells and tight control of their differentiation into a permanent cartilage phenotype. Bone morphogenetic protein 2 (BMP‐2) has been extensively shown to promote mesenchymal cell differ...

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Detalles Bibliográficos
Autores principales: Gibson, Jason D., O'Sullivan, Michael B., Alaee, Farhang, Paglia, David N., Yoshida, Ryu, Guzzo, Rosa M., Drissi, Hicham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442752/
https://www.ncbi.nlm.nih.gov/pubmed/28170184
http://dx.doi.org/10.5966/sctm.2016-0020