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Regeneration of Articular Cartilage by Human ESC‐Derived Mesenchymal Progenitors Treated Sequentially with BMP‐2 and Wnt5a
The success of cell‐based therapies to restore joint cartilage requires an optimal source of reparative progenitor cells and tight control of their differentiation into a permanent cartilage phenotype. Bone morphogenetic protein 2 (BMP‐2) has been extensively shown to promote mesenchymal cell differ...
Autores principales: | Gibson, Jason D., O'Sullivan, Michael B., Alaee, Farhang, Paglia, David N., Yoshida, Ryu, Guzzo, Rosa M., Drissi, Hicham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442752/ https://www.ncbi.nlm.nih.gov/pubmed/28170184 http://dx.doi.org/10.5966/sctm.2016-0020 |
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