Directed Differentiation of Human Embryonic Stem Cells Toward Placode‐Derived Spiral Ganglion‐Like Sensory Neurons

The ability to generate spiral ganglion neurons (SGNs) from stem cells is a necessary prerequisite for development of cell‐replacement therapies for sensorineural hearing loss. We present a protocol that directs human embryonic stem cells (hESCs) toward a purified population of otic neuronal progeni...

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Detalles Bibliográficos
Autores principales: Matsuoka, Akihiro J., Morrissey, Zachery D., Zhang, Chaoying, Homma, Kazuaki, Belmadani, Abdelhak, Miller, Charles A., Chadly, Duncan M., Kobayashi, Shun, Edelbrock, Alexandra N., Tanaka‐Matakatsu, Miho, Whitlon, Donna S., Lyass, Ljuba, McGuire, Tammy L., Stupp, Samuel I., Kessler, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442760/
https://www.ncbi.nlm.nih.gov/pubmed/28186679
http://dx.doi.org/10.1002/sctm.16-0032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442760/
https://www.ncbi.nlm.nih.gov/pubmed/28186679
http://dx.doi.org/10.1002/sctm.16-0032

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