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Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction

Human umbilical cord blood‐derived mesenchymal stem cells (hUCB‐MSCs) exhibit potency for the regeneration of infarcted hearts. Vascular endothelial growth factor (VEGF) is capable of inducing angiogenesis and can boost stem cell‐based therapeutic effects. However, high levels of VEGF can cause abno...

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Detalles Bibliográficos
Autores principales: Cho, Hyun‐Min, Kim, Pyung‐Hwan, Chang, Hyun‐Kyung, Shen, Yi‐ming, Bonsra, Kwaku, Kang, Byung‐Jae, Yum, Soo‐Young, Kim, Joo‐Hyun, Lee, So‐Yeong, Choi, Min‐cheol, Kim, Hyongbum (Henry), Jang, Goo, Cho, Je‐Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442764/
https://www.ncbi.nlm.nih.gov/pubmed/28186692
http://dx.doi.org/10.1002/sctm.16-0114