Gamma‐Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt‐Beta‐Catenin Pathways in CD44(+) Gastric Cancer Stem Cells

Cancer stem cells (CSC) are associated with tumor resistance and are characterized in gastric cancer (GC). Studies have indicated that Notch and wnt‐beta‐catenin pathways are crucial for CSC development. Using CD44(+) CSCs, we investigated the role of these pathways in GC carcinogenesis. We performe...

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Detalles Bibliográficos
Autores principales: Barat, Samarpita, Chen, Xi, Cuong Bui, Khac, Bozko, Przemyslaw, Götze, Julian, Christgen, Matthias, Krech, Till, Malek, Nisar P., Plentz, Ruben R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442767/
https://www.ncbi.nlm.nih.gov/pubmed/28186678
http://dx.doi.org/10.1002/sctm.16-0335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442767/
https://www.ncbi.nlm.nih.gov/pubmed/28186678
http://dx.doi.org/10.1002/sctm.16-0335

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