Cargando…
Gamma‐Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt‐Beta‐Catenin Pathways in CD44(+) Gastric Cancer Stem Cells
Cancer stem cells (CSC) are associated with tumor resistance and are characterized in gastric cancer (GC). Studies have indicated that Notch and wnt‐beta‐catenin pathways are crucial for CSC development. Using CD44(+) CSCs, we investigated the role of these pathways in GC carcinogenesis. We performe...
Autores principales: | Barat, Samarpita, Chen, Xi, Cuong Bui, Khac, Bozko, Przemyslaw, Götze, Julian, Christgen, Matthias, Krech, Till, Malek, Nisar P., Plentz, Ruben R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442767/ https://www.ncbi.nlm.nih.gov/pubmed/28186678 http://dx.doi.org/10.1002/sctm.16-0335 |
Ejemplares similares
-
Epithelial Mesenchymal Transition and Pancreatic Tumor Initiating CD44+/EpCAM+ Cells Are Inhibited by γ-Secretase Inhibitor IX
por: Palagani, Vindhya, et al.
Publicado: (2012) -
Capsaicin Treatment Attenuates Cholangiocarcinoma Carcinogenesis
por: Wutka, Annika, et al.
Publicado: (2014) -
Correction: Capsaicin Treatment Attenuates Cholangiocarcinoma Carcinogenesis
por: Wutka, Annika, et al.
Publicado: (2016) -
Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo
por: El Khatib, Mona, et al.
Publicado: (2013) -
Correction: Activation of Notch Signaling Is Required for Cholangiocarcinoma Progression and Is Enhanced by Inactivation of p53 In Vivo
por: El Khatib, Mona, et al.
Publicado: (2018)