Safety and Efficacy of Megakaryocytes Induced from Hematopoietic Stem Cells in Murine and Nonhuman Primate Models

Because of a lack of platelet supply and a U.S. Food and Drug Administration‐approved platelet growth factor, megakaryocytes have emerged as an effective substitute for alleviating thrombocytopenia. Here, we report the development of an efficient two‐stage culture system that is free of stroma, anim...

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Detalles Bibliográficos
Autores principales: Guan, Xin, Qin, Meng, Zhang, Yu, Wang, Yanan, Shen, Bin, Ren, Zhihua, Ding, Xinxin, Dai, Wei, Jiang, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442772/
https://www.ncbi.nlm.nih.gov/pubmed/28297572
http://dx.doi.org/10.5966/sctm.2016-0224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442772/
https://www.ncbi.nlm.nih.gov/pubmed/28297572
http://dx.doi.org/10.5966/sctm.2016-0224

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