Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno‐Free Conditions Restore Motor Deficits in Parkinsonian Rodents

Recent studies have shown evidence for the functional integration of human pluripotent stem cell (hPSC)‐derived ventral midbrain dopamine (vmDA) neurons in animal models of Parkinson’s disease. Although these cells present a sustainable alternative to fetal mesencephalic grafts, a number of hurdles...

Descripción completa

Detalles Bibliográficos
Autores principales: Niclis, Jonathan C., Gantner, Carlos W., Alsanie, Walaa F., McDougall, Stuart J., Bye, Chris R., Elefanty, Andrew G., Stanley, Edouard G., Haynes, John M., Pouton, Colin W., Thompson, Lachlan H., Parish, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Translational Research Articles and Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442782/
https://www.ncbi.nlm.nih.gov/pubmed/28297587
http://dx.doi.org/10.5966/sctm.2016-0073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442782/
https://www.ncbi.nlm.nih.gov/pubmed/28297587
http://dx.doi.org/10.5966/sctm.2016-0073

Ejemplares similares