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EpCAM+ Liver Cancer Stem‐Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic Patients

Hepatocellular carcinoma (HCC) is believed to originate from cancer stem cells (CSCs). While epithelial cell adhesion molecule (EpCAM) is a marker of normal hepatic stem cells (HSCs), EpCAM+ cells from HCC behave like CSCs. Since HCC mostly develops on a cirrhotic background, we sought to determine...

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Detalles Bibliográficos
Autores principales: Khosla, Ritu, Rastogi, Archana, Ramakrishna, Gayatri, Pamecha, Viniyendra, Mukhopadhyay, Ashok, Vasudevan, Madavan, Sarin, Shiv Kumar, Trehanpati, Nirupma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442787/
https://www.ncbi.nlm.nih.gov/pubmed/28176469
http://dx.doi.org/10.1002/sctm.16-0248