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Generation of Osteosarcomas from a Combination of Rb Silencing and c‐Myc Overexpression in Human Mesenchymal Stem Cells

Osteosarcoma (OS) was a malignant tumor occurring with unknown etiology that made prevention and early diagnosis difficult. Mesenchymal stem cells (MSCs), which were found in bone marrow, were claimed to be a possible origin of OS but with little direct evidence. We aimed to characterize OS cells tr...

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Detalles Bibliográficos
Autores principales: Wang, Jir‐You, Wu, Po‐Kuei, Chen, Paul Chih‐Hsueh, Lee, Chia‐Wen, Chen, Wei‐Ming, Hung, Shih‐Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442803/
https://www.ncbi.nlm.nih.gov/pubmed/28191765
http://dx.doi.org/10.5966/sctm.2015-0226