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Direct Isolation and Characterization of Human Nephron Progenitors

Mature nephrons originate from a small population of uninduced nephrogenic progenitor cells (NPs) within the cap mesenchyme. These cells are characterized by the coexpression of SIX2 and CITED1. Many studies on mouse models as well as on human pluripotent stem cells have advanced our knowledge of NP...

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Detalles Bibliográficos
Autores principales: Da Sacco, Stefano, Thornton, Matthew E., Petrosyan, Astgik, Lavarreda‐Pearce, Maria, Sedrakyan, Sargis, Grubbs, Brendan H., De Filippo, Roger E., Perin, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442819/
https://www.ncbi.nlm.nih.gov/pubmed/28191781
http://dx.doi.org/10.5966/sctm.2015-0429