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Notch‐Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients

The hematopoietic syndrome of acute radiation syndrome (h‐ARS) is characterized by severe bone marrow aplasia, resulting in a significant risk for bleeding, infections, and death. To date, clinical management of h‐ARS is limited to supportive care dictated by the level of radiation exposure, with a...

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Detalles Bibliográficos
Autores principales: Milano, Filippo, Merriam, Fabiola, Nicoud, Ian, Li, Jianqiang, Gooley, Ted A., Heimfeld, Shelly, Imren, Suzan, Delaney, Colleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442821/
https://www.ncbi.nlm.nih.gov/pubmed/28191773
http://dx.doi.org/10.5966/sctm.2016-0112