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Notch‐Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients
The hematopoietic syndrome of acute radiation syndrome (h‐ARS) is characterized by severe bone marrow aplasia, resulting in a significant risk for bleeding, infections, and death. To date, clinical management of h‐ARS is limited to supportive care dictated by the level of radiation exposure, with a...
Autores principales: | Milano, Filippo, Merriam, Fabiola, Nicoud, Ian, Li, Jianqiang, Gooley, Ted A., Heimfeld, Shelly, Imren, Suzan, Delaney, Colleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442821/ https://www.ncbi.nlm.nih.gov/pubmed/28191773 http://dx.doi.org/10.5966/sctm.2016-0112 |
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