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Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup

BACKGROUND: Parent-offspring (PO) regression is a central tool to determine the heritability of phenotypic traits; i.e., the relative extent to which those traits are controlled by genetic factors. The applicability of PO regression to viral traits is unclear because the direction of viral transmiss...

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Detalles Bibliográficos
Autores principales: Bachmann, Nadine, Turk, Teja, Kadelka, Claus, Marzel, Alex, Shilaih, Mohaned, Böni, Jürg, Aubert, Vincent, Klimkait, Thomas, Leventhal, Gabriel E., Günthard, Huldrych F., Kouyos, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442860/
https://www.ncbi.nlm.nih.gov/pubmed/28535768
http://dx.doi.org/10.1186/s12977-017-0356-3