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Effects of caffeine on cell viability and activity of histone deacetylase 1 and histone acetyltransferase in glioma cells

OBJECTIVE: The prognosis of patients with glioblastoma remains poor even after various treatments such as surgery, radiotherapy, and chemotherapy. Thus, development of new drugs is urgently needed. The mechanisms underlying the cytotoxicity of caffeine in glioma cells are not clearly understood. Thi...

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Detalles Bibliográficos
Autores principales: Chen, Jin-Cherng, Hwang, Juen-Haur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442913/
https://www.ncbi.nlm.nih.gov/pubmed/28757735
http://dx.doi.org/10.1016/j.tcmj.2016.06.005