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Pharmacokinetic and Pharmacodynamic Efficacies of Continuous versus Intermittent Administration of Meropenem in Patients with Severe Sepsis and Septic Shock: A Prospective Randomized Pilot Study

BACKGROUND: The antibiotic meropenem is commonly administered in patients with severe sepsis and septic shock. We compared the pharmacokinetic, clinical, and bacteriological efficacies of continuous infusion of meropenem versus intermittent administration in such patients. METHODS: Patients admitted...

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Detalles Bibliográficos
Autores principales: Zhao, Hui-Ying, Gu, Jian, Lyu, Jie, Liu, Dan, Wang, Yi-Tong, Liu, Fang, Zhu, Feng-Xue, An, You-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443018/
https://www.ncbi.nlm.nih.gov/pubmed/28485312
http://dx.doi.org/10.4103/0366-6999.205859