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Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitro
The aim of the present study was to investigate the correlation between glucocorticoid activity regulation, prostaglandin E2 (PGE(2)) synthesis, and synovial inflammation inhibition activity, through microsomal prostaglandin E synthase-1 (mPGES-1) expression regulated by the glucocorticoid pre-recep...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443184/ https://www.ncbi.nlm.nih.gov/pubmed/28565823 http://dx.doi.org/10.3892/etm.2017.4238 |