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Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitro

The aim of the present study was to investigate the correlation between glucocorticoid activity regulation, prostaglandin E2 (PGE(2)) synthesis, and synovial inflammation inhibition activity, through microsomal prostaglandin E synthase-1 (mPGES-1) expression regulated by the glucocorticoid pre-recep...

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Detalles Bibliográficos
Autores principales: Wei, Bo, Zhu, Zhaobo, Xiang, Min, Song, Lijun, Guo, Weixiong, Lin, Hao, Li, Guangsheng, Zeng, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443184/
https://www.ncbi.nlm.nih.gov/pubmed/28565823
http://dx.doi.org/10.3892/etm.2017.4238