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Autophagy activated by the c-Jun N-terminal kinase-mediated pathway protects human prostate cancer PC3 cells from celecoxib-induced apoptosis

The aim of the present study was to investigate the role of autophagy in celecoxib-induced apoptosis in human hormone-insensitive prostate cancer cell line PC3 cells and to explore the underlying molecular mechanism leading to autophagic activation. A cell viability assay was applied to investigate...

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Detalles Bibliográficos
Autores principales: Zhu, Xin, Zhou, Mi, Liu, Guanyu, Huang, Xiaolong, He, Weiyang, Gou, Xin, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443255/
https://www.ncbi.nlm.nih.gov/pubmed/28565848
http://dx.doi.org/10.3892/etm.2017.4287