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Correlation between PKB/Akt, GSK-3β expression and tubular epithelial-mesenchymal transition in renal allografts with chronic active antibody-mediated rejection

Chronic antibody-mediated rejection (ABMR) is a major cause of the transplant renal interstitial fibrosis and transplanted kidney epithelial cell transdifferentiation is one of the main mechanisms. The transforming growth factor (TGF)-β1/integrin-linked kinase (ILK) signaling pathway has a significa...

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Detalles Bibliográficos
Autores principales: Yan, Qiang, Luo, Hao, Wang, Baoyao, Sui, Weiguo, Zou, Guimian, Chen, Huaizhou, Zou, Hequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443285/
https://www.ncbi.nlm.nih.gov/pubmed/28565830
http://dx.doi.org/10.3892/etm.2017.4261