Cargando…

MitoKATP regulating HIF/miR210/ISCU signaling axis and formation of a positive feedback loop in chronic hypoxia-induced PAH rat model

In the present study, we studied the mechanism of mitochondrial ATP-sensitive potassium (mitoKATP) channels regulating hypoxia-inducible factor (HIF)-1α/microRNA (miR)-210/mitochondrial iron-sulfur protein integrin (ISCU) signaling axis and forming a positive feedback loop in chronic hypoxia-induced...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yang, Huang, Jing, Geng, Shuang, Chen, Hao, Song, Cheng, Zhu, Shan, Zhao, Su, Yuan, Mingli, Li, Xueying, Hu, Hongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443288/
https://www.ncbi.nlm.nih.gov/pubmed/28565755
http://dx.doi.org/10.3892/etm.2017.4161