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Differential expression of islet glutaredoxin 1 and 5 with high reactive oxygen species production in a mouse model of diabesity

The onset and progression of diabetes mellitus type 2 is highly contingent on the amount of functional beta-cell mass. An underlying cause of beta-cell decay in diabetes is oxidative stress, which markedly affects the insulin producing pancreatic cells due to their poor antioxidant defence capacity....

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Detalles Bibliográficos
Autores principales: Petry, Sebastian Friedrich, Sharifpanah, Fatemeh, Sauer, Heinrich, Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443478/
https://www.ncbi.nlm.nih.gov/pubmed/28542222
http://dx.doi.org/10.1371/journal.pone.0176267