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Differential expression of islet glutaredoxin 1 and 5 with high reactive oxygen species production in a mouse model of diabesity
The onset and progression of diabetes mellitus type 2 is highly contingent on the amount of functional beta-cell mass. An underlying cause of beta-cell decay in diabetes is oxidative stress, which markedly affects the insulin producing pancreatic cells due to their poor antioxidant defence capacity....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443478/ https://www.ncbi.nlm.nih.gov/pubmed/28542222 http://dx.doi.org/10.1371/journal.pone.0176267 |