Cargando…
Binding of CIB1 to the α(IIb) tail of α(IIb)β(3) is required for FAK recruitment and activation in platelets
BACKGROUND: It is believed that activation of c-Src bound to the integrin β(3) subunit initiates outside-in signaling. The involvement of α(IIb) in outside-in signaling is poorly understood. OBJECTIVES: We have previously shown that CIB1 specifically interacts with the cytoplasmic domain of α(IIb) a...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443481/ https://www.ncbi.nlm.nih.gov/pubmed/28542214 http://dx.doi.org/10.1371/journal.pone.0176602 |