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In vivo transduction of neurons with TAT-UCH-L1 protects brain against controlled cortical impact injury
Many mechanisms or pathways are involved in secondary post-traumatic brain injury, such as the ubiquitin-proteasome pathway (UPP), axonal degeneration and neuronal cell apoptosis. UCH-L1 is a protein that is expressed in high levels in neurons and may have important roles in the UPP, autophagy and a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443532/ https://www.ncbi.nlm.nih.gov/pubmed/28542502 http://dx.doi.org/10.1371/journal.pone.0178049 |