Cargando…

In vivo transduction of neurons with TAT-UCH-L1 protects brain against controlled cortical impact injury

Many mechanisms or pathways are involved in secondary post-traumatic brain injury, such as the ubiquitin-proteasome pathway (UPP), axonal degeneration and neuronal cell apoptosis. UCH-L1 is a protein that is expressed in high levels in neurons and may have important roles in the UPP, autophagy and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Hao, Rose, Marie E., Ma, Xiecheng, Culver, Sherman, Dixon, C. Edward, Graham, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443532/
https://www.ncbi.nlm.nih.gov/pubmed/28542502
http://dx.doi.org/10.1371/journal.pone.0178049