Robustness analysis of the detailed kinetic model of an ErbB signaling network by using dynamic sensitivity

The ErbB receptor signaling pathway plays an important role in the regulation of cellular proliferation, survival and differentiation, and dysregulation of the pathway is linked to various types of human cancer. Mathematical models have been developed as a practical complementary approach to deciphe...

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Detalles Bibliográficos
Autores principales: Masunaga, Hiroyuki, Sugimoto, Yurie, Magi, Shigeyuki, Itasaki, Ryunosuke, Okada-Hatakeyama, Mariko, Kurata, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443533/
https://www.ncbi.nlm.nih.gov/pubmed/28542548
http://dx.doi.org/10.1371/journal.pone.0178250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443533/
https://www.ncbi.nlm.nih.gov/pubmed/28542548
http://dx.doi.org/10.1371/journal.pone.0178250

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