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Robustness analysis of the detailed kinetic model of an ErbB signaling network by using dynamic sensitivity
The ErbB receptor signaling pathway plays an important role in the regulation of cellular proliferation, survival and differentiation, and dysregulation of the pathway is linked to various types of human cancer. Mathematical models have been developed as a practical complementary approach to deciphe...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443533/ https://www.ncbi.nlm.nih.gov/pubmed/28542548 http://dx.doi.org/10.1371/journal.pone.0178250 |