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Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB

In bacteria, double-strand break (DSB) repair via homologous recombination is thought to be initiated through the bi-directional degradation and resection of DNA ends by a helicase-nuclease complex such as AddAB. The activity of AddAB has been well-studied in vitro, with translocation speeds between...

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Detalles Bibliográficos
Autores principales: Badrinarayanan, Anjana, Le, Tung B. K., Spille, Jan-Hendrik, Cisse, Ibrahim I., Laub, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443536/
https://www.ncbi.nlm.nih.gov/pubmed/28489851
http://dx.doi.org/10.1371/journal.pgen.1006783