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Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB
In bacteria, double-strand break (DSB) repair via homologous recombination is thought to be initiated through the bi-directional degradation and resection of DNA ends by a helicase-nuclease complex such as AddAB. The activity of AddAB has been well-studied in vitro, with translocation speeds between...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443536/ https://www.ncbi.nlm.nih.gov/pubmed/28489851 http://dx.doi.org/10.1371/journal.pgen.1006783 |